Nephrology News

Urine neutrophil gelatinase-associated lipocalin and other biomarkers in infants with urinary tract infection and in febrile controls

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ConclusionsUrine biomarkers, particularly NGAL, can aid in the diagnosis of UTI among febrile infants. The results suggest that in infants with fever and high NGAL, UTI is most likely, whereas in infants with fever and low NGAL, other causes of fever should be looked for.

Conclusion In this PMS, the safety and efficacy profiles of canagliflozin in elderly patients with T2DM were obtained in the clinical settings in Japan, and the drug was well tolerated and effective in improving glycemic control. PMID: 29025285 [PubMed - as supplied by publisher]

CONCLUSION: Escherichia coli was the prevailing bacterial infections among those which were isolated from patients with UTI. Certain forms of bacterial infections inclined to be extra common in diabetic patients than others and other infections may be more severe in people with diabetics than in non diabetics. PMID: 29023074 [PubMed - in process]

Source: Pakistan Journal of Biological Sciences: PJBS - October 14, 2017Category: Biomedical Science Authors: Al-Asoufi A, Khlaifat A, Tarawneh AA, Alsharafa K, Al-Limoun M, Khleifat K Tags: Pak J Biol Sci Source Type: research

CONCLUSION: Klebsiella pneumoniae strains isolated from burns infections were more virulent than those isolated from urinary tract infections. PMID: 29023034 [PubMed - in process]

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Source: Infectious Diseases - October 14, 2017Category: Infectious Diseases Authors: Kalid Bouaghroum Pierre-Luc Genillier Dominique Neri Djamel Lameche Matteo Vassallo Source Type: research

Publication date: Available online 13 October 2017 Source:Journal of Pediatric Surgery Case Reports Author(s): Il Kyoon Kim, Ranjith Vellody, Hans G. Pohl, Karun Sharma, Bhupender Yadav Pyometrocolpos can be caused by congenital malformations such as distal vaginal atresia and imperforate hymen. Patients usually present with obstructive urinary tract infections, acute kidney injury, or sepsis. Percutaneous drainage of the infected fluid can help treat the patient; however, recurrence is of concern. In this case report, we present a case of a child with recurrent pyometrocolpos due to distal vaginal atresia despite initial...

BackgroundParalysis is a known risk factor for urinary tract infections (UTI), sepsis, and death in paralyzed people, but there are no data available on diagnostic criteria for UTI versus bacteriuria, their frequency, or clinical implications in chronically paralyzed dogs. Hypothesis/ObjectivesThat chronically paralyzed dogs suffer frequent bacteriuria causing reduced duration of survival. We documented the frequency of bacteriuria, associated clinical signs, and survival rate in chronically paralyzed dogs. AnimalsForty‐seven client‐owned dogs paralyzed with no pelvic limb pain perception for>3 months and at le...

ConclusionFunctional variants in intercellular adhesion molecule‐1 and toll‐like receptor‐4 genes were increasingly common in children with febrile UTIs with renal parenchymal involvement, but the ICAM‐1 Glu469Lys (1462A/G) association was less evident. TLR4 Asp299Gly might independently increase renal parenchymal infection rather than renal scarring.This article is protected by copyright. All rights reserved.

Source: Acta Paediatrica - October 13, 2017Category: Pediatrics Authors: Almontaser Hussein, Khaled Saad, Eman Askar, Asmaa M. Zahran, Hekma Farghaly, Kotb Metwalley, Ahmad A Elderwy Tags: Regular Article Source Type: research

We report a retrospective monocentric descriptive study performed in CHI Creteil for 20 months to describe the management and outcome of amikacin monotherapy as an alternative to third-generation cephalosporins for empiric treatment of febrile urinary tract infection (FUTI) in children. Data were analyzed for 151 children, and 90 selected cases were classified as certain or highly probable FUTI. Escherichia coli infection was found in 89 cases. In all patients, fever was resolved within 72 hours after beginning amikacin treatment. Only 5.3% of children were febrile after 48 hours. The mean amikacin treatment duration was 3...

CONCLUSIONS: Endogenous endophthalmitis usually has a poor visual prognosis. Liver abscess and urinary tract infections are common primary sites of infection. Poor initial visual acuity and severe intraocular inflammation at the initial presentation are predictors of poor visual outcome. PMID: 29020471 [PubMed - as supplied by publisher]

CONCLUSIONS: ESBL producing E. coli and K. pneumoniae were prevalent, especially the latter, with a significant resistance to ciprofloxacin and cotrimoxazole. Susceptibility to imipenem was high. PMID: 28992981 [PubMed - as supplied by publisher]

Source: Medicina Clinica - October 12, 2017Category: General Medicine Tags: Med Clin (Barc) Source Type: research

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