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Nephrology News

Galen Care Partners

High, Low Values of CKD-MBD Markers Linked With Mortality

In a study, intact parathyroid hormone levels below 60 and above 1500 pg/mL were associated with nearly double the risk of all-cause mortality.
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Acute Kidney Injury in CCU Patients Linked to Cystatin C

Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.
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2119 Hits
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Diabetic CKD Patients Survive Longer With Metformin

Diabetic patients with chronic kidney disease starting treatment with metformin have a 36% decreased risk of death compared with those starting on a sulfonylurea, study finds.
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2064 Hits
Galen Care Partners

Medication Discrepancies Common in Advanced CKD

In a study, taking a medication not on a nephrologists' list, not taking a specified medication, taking different doses, or following a different frequency topped the list.
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2253 Hits
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Adults being diagnosed with the wrong diabetes, study finds

Helen Philibin
Image copyright Helen PhilibinImage caption Helen Philibin was misdiagnosed with Type 2 diabetes

Many might think type 1 diabetes is a "disease of childhood", but research, published in the Lancet Diabetes & Endocrinology, has found it has similar prevalence in adults.

More than 40% of Britons diagnosed with the condition are over 30.

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2051 Hits
Galen Care Partners

Cytoreductive Nephrectomy Improves Survival in mRCC

Propensity score matching showed a 5.8 month survival advantage for initial CN vs initial systematic therapy.
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Ethanol Ablation Therapy Feasible for SHPT

In a small study, more than half of patients with secondary hyperparathyroidism had a greater than 25% drop in parathyroid hormone levels following ethanol injection therapy.
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Galen Care Partners

Hypocalcemia Common After Cinacalcet Initiation

Hypocalcemia developed in 58.3% of study participants within the first 16 weeks and, in most cases, resolved within 14 days with no changes in treatment.
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2165 Hits
Galen Care Partners

SHPT Highly Prevalent Among Diabetic Nephropathy Patients

Nearly 86% of diabetic nephropathy patients from an Egyptian outpatient center had elevated iPTH levels.
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Galen Care Partners

High Uric Acid Ups Renal Failure Risk in Some CKD Patients

Among CKD patients with an eGFR of 45 mL/min/1.73 m2 or above, each 1 SD increase in baseline uric acid levels is independently associated with a 40% increased risk of kidney failure.
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2291 Hits
Galen Care Partners

SHPT Highly Prevalent Among Diabetic Nephropathy Patients

Nearly 86% of diabetic nephropathy patients from an Egyptian outpatient center had elevated iPTH levels.
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2087 Hits
Galen Care Partners

Metabolites altered in chronic kidney disease

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK). These individuals have a very high risk of cardiovascular disease, and some will also progress to kidney failure requiring dialysis and transplantation.

However, few options exist to treat them, and few major breakthroughs have been made during the last 30 years. More than 660,000 Americans have kidney failure, according to the NIDDK.

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Lithium Therapy May Not Increase ESRD Risk

In the subcohorts of patients with a diagnosis of bipolar disorder, continuing lithium was associated with decreased end-stage CKD, whereas continuing anticonvulsants was not.
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2075 Hits
Galen Care Partners

FDA Approves Sunitinib for Adjuvant Treatment of RCC

At 5 years, 59.3% of patients treated with sunitinib were free from recurrence versus 51.3% who received placebo.
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2363 Hits
Galen Care Partners

New Model Improves Predictions of Advanced CKD Following AKI

The model was based on 6 variables readily obtained at hospital discharge.
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2055 Hits
Galen Care Partners

Point-of-Care Ultrasound Helps Detect Stones

Complication rates were no higher with point-of-care ultrasound than CT.
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2232 Hits
Galen Care Partners

Review Highlights Nutritional Management of CKD

A low-protein diet, for example, may slow disease progression.
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2256 Hits
Galen Care Partners

Tolvaptan Slows Renal Function Decline in Later-Stage ADPKD

Patients with autosomal dominant polycystic kidney disease treated with tolvaptan experienced a 35% decrease in the annual rate of decline in eGFR.
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2300 Hits
Galen Care Partners

Causes of Most Kidney Transplant Patient Deaths Reported as Unknown

Among kidney transplant recipients who died with a functioning graft, the cause of death was reported as unknown for 64% of them.
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2073 Hits
Galen Care Partners

Higher Relative Urine Supersaturations Up Stone Risk

Likelihood of stone formation increases with higher calcium oxalate and calcium phosphate relative supersaturation.
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