Nephrology News

AS Safe for Cystic Renal Masses in Selected Patients

In a single-center study, 24% of patients crossed over to treatment and 95% of patients were alive after 5 years of follow-up.
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AS Safe for Cystic Renal Masses in Selected Patients

In a single-center study, 24% of patients crossed over to treatment and 95% of patients were alive after 5 years of follow-up.
Continue reading

Nomogram Developed to Predict Ureteral Stone Passage

Likelihood of stone passage in patients on medical expulsive therapy is based on variables such as stone size and location and white blood cell count.
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Stone Formation Linked to Hemoglobin A1c Levels

Finding could explain the association between obesity and diabetes and the development of kidney stones.
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Kidney research leads to surprising discovery about how the heart forms

Kidney research at the University of Virginia School of Medicine has unexpectedly led to a discovery about the formation of the heart, including the identification of a gene responsible for a deadly cardiac condition.

UVA scientists were surprised to discover that the heart's inner lining forms from the same stem cells, known as "precursor cells," that turn into blood. That means a single type of stem cell turns into both our blood and a portion of the organ that will pump it.

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Why Everything We Know About Salt May Be Wrong

Research on Russian cosmonauts suggests that salt makes you hungry but not thirsty, and may help burn calories.
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Studies reveal socioeconomic and racial disparities in lupus

Two new studies have uncovered socioeconomic disparities related to the health of patients with lupus. A study in Arthritis & Rheumatology found a link between poverty and worse disease-associated medical complications over time, and a study in Arthritis Care & Research discovered that the frequency of adverse pregnancy outcomes in Black and Hispanic patients with lupus is higher than that in White women with the disease.

To estimate the effect of poverty on damage to organ systems in patients with lupus, Edward Yelin, PhD, of the University of California, San Francisco, and his colleagues followed 783 patients from 2003 to 2015 through annual interviews. Respondents were categorized in each year by whether they were in households ≤125% of the Federal Poverty Level.

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NSAIDs may raise heart attack risk in first week of use

[Anti-inflammatory drugs]
When headache or back pain strikes, many of us turn to ibuprofen for some quick relief. A new study, however, finds that using this and other classes of nonsteroidal anti-inflammatory drugs for as little as 1 week may increase the risk of heart attack.

Researchers have found that NSAIDs pose the greatest heart attack risk in the first month of use.

Study leader Michèle Bally, of the University of Montreal Hospital Research Center in Canada, and colleagues recently reported their findings in The BMJ.

According to the Centers for Disease Control and Prevention (CDC), every year, around 735,000 people in the United States have a heart attack, otherwise known as myocardial infarction.

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Obese Women Less Likely to Suffer from Dangerous Preeclampsia Complications

Obese Women Less Likely to Suffer from Dangerous Preeclampsia Complications Penn obstetricians uncover better ways to assess risk of complications caused by preeclampsia during pregnancy

Newswise — SAN DIEGO, CA — Despite having higher rates of preeclampsia, a dangerous high-blood pressure disorder of late pregnancy, obese women may be less than half as likely to suffer strokes, seizures, and other serious complications of the disorder. The findings are among those from two new studies of preeclampsia by researchers at the Perelman School of Medicine at University of Pennsylvania showing how obesity may help clinicians identify risk for the condition or other complications. The second study highlighted risk factors, including obesity, for persistent high blood pressure after delivery among women with preeclampsia. The studies (posters 31C and 20B, respectively) will be presented at the American Congress of Obstetricians & Gynecologists' (ACOG) Annual Clinical and Scientific Meeting in San Diego.

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Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

In a study, obese transplant recipients with low muscle mass had an increased risk of death but not graft loss.
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Simple blood tests lead to improved hypertension treatment in African countries

Using two simple blood tests, Western University researchers were able to drastically improve treatment for resistant hypertension across three sites in Nigeria, Kenya and South Africa.

The study, published online in the American Journal of Hypertension, demonstrates that for patients in Africa with hard-to-control hypertension, identifying the cause was the key to lowering blood pressure. By testing patients' levels of plasma renin, a protein secreted by the kidneys, in combination with levels of aldosterone, a hormone that causes salt and water retention, physicians were able to identify the physiological changes causing the hypertension. This led to personalized and more accurate therapy.

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Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

In a study, obese transplant recipients with low muscle mass had an increased risk of death but not graft loss.
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Surprising link between blood sugar, brain cancer found

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.

While many cancers are more common among those with diabetes, cancerous brain tumors called gliomas are less common among those with elevated blood sugar and diabetes, a study from The Ohio State University has found.

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Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.
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NODAT Risk Similar After Switching From CNIs to Everolimus

The incidence of NODAT was 33.8% among patients who switched to everolimus and 36.4% among those who stayed on calcineurin inhibitors.
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Post-Transplant Infections, Cancer Do Not Up Mortality

Opportunistic viral and fungal infections or malignancies develop in 34% of kidney transplant recipients, but these complications do not affect patient or graft survival.
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Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, respectively.
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Diabetes Increases Post-Transplant Mortality Risk

In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.
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Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.
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Bacteremia Worsens Kidney Transplant Outcomes

Kidney transplant recipients who experienced an episode of bacteremia had double the risks of graft failure and death.
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