Kidney research at the University of Virginia School of Medicine has unexpectedly led to a discovery about the formation of the heart, including the identification of a gene responsible for a deadly cardiac condition.
UVA scientists were surprised to discover that the heart's inner lining forms from the same stem cells, known as "precursor cells," that turn into blood. That means a single type of stem cell turns into both our blood and a portion of the organ that will pump it.
Two new studies have uncovered socioeconomic disparities related to the health of patients with lupus. A study in Arthritis & Rheumatology found a link between poverty and worse disease-associated medical complications over time, and a study in Arthritis Care & Research discovered that the frequency of adverse pregnancy outcomes in Black and Hispanic patients with lupus is higher than that in White women with the disease.
To estimate the effect of poverty on damage to organ systems in patients with lupus, Edward Yelin, PhD, of the University of California, San Francisco, and his colleagues followed 783 patients from 2003 to 2015 through annual interviews. Respondents were categorized in each year by whether they were in households ≤125% of the Federal Poverty Level.
Study leader Michèle Bally, of the University of Montreal Hospital Research Center in Canada, and colleagues recently reported their findings in The BMJ.
Obese Women Less Likely to Suffer from Dangerous Preeclampsia Complications Penn obstetricians uncover better ways to assess risk of complications caused by preeclampsia during pregnancy
Newswise — SAN DIEGO, CA — Despite having higher rates of preeclampsia, a dangerous high-blood pressure disorder of late pregnancy, obese women may be less than half as likely to suffer strokes, seizures, and other serious complications of the disorder. The findings are among those from two new studies of preeclampsia by researchers at the Perelman School of Medicine at University of Pennsylvania showing how obesity may help clinicians identify risk for the condition or other complications. The second study highlighted risk factors, including obesity, for persistent high blood pressure after delivery among women with preeclampsia. The studies (posters 31C and 20B, respectively) will be presented at the American Congress of Obstetricians & Gynecologists' (ACOG) Annual Clinical and Scientific Meeting in San Diego.
Using two simple blood tests, Western University researchers were able to drastically improve treatment for resistant hypertension across three sites in Nigeria, Kenya and South Africa.
The study, published online in the American Journal of Hypertension, demonstrates that for patients in Africa with hard-to-control hypertension, identifying the cause was the key to lowering blood pressure. By testing patients' levels of plasma renin, a protein secreted by the kidneys, in combination with levels of aldosterone, a hormone that causes salt and water retention, physicians were able to identify the physiological changes causing the hypertension. This led to personalized and more accurate therapy.
New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop.
While many cancers are more common among those with diabetes, cancerous brain tumors called gliomas are less common among those with elevated blood sugar and diabetes, a study from The Ohio State University has found.