Nephrology News

ESRD Risk Higher in SLE Patients Hospitalized for Infections

End-stage renal disease is 5-fold more likely to develop in patients with 3 or more infection-related hospitalizations versus none.
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Sirukumab Ineffective in Lupus Nephritis

The primary outcome was reduction in proteinuria, as measured by protein-to-creatinine (P:C) ratio in a 12-hour urine collection, at 24 weeks compared with baseline.
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Urinary Biomarker Index Measures LN Activity Without Biopsy

The development of this scale, once further validated, will give clinicians the ability to verify lupus nephritis activity without the need for an invasive kidney biopsy.
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SLE Renal Outcomes for Mixed LN vs Pure Proliferative LN

Among the findings, researchers found no association between mixed or pure histopathologic features of LN at presentation and rates of complete or partial remission.
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Lupus Nephritis ESRD Has Worse Outcomes

Researchers find an increased risk of death among patients.
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Acthar Gel May Be an Option for Nephrotic Syndrome

Athcar gel may be a treatment option for patients with treatment-resistant nephrotic syndrome.
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Proteinuric Remission in Lupus Nephritis Predicts Better Outcomes

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Mycophenolate Mofetil Offers No Advantage in Lupus Nephritis

New study also provides evidence that an early proteinuria decrease is a strong predictor of good long-term outcome.
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Black Patients with Lupus Nephritis and ESRD Have Higher CV Risks

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Lupus Nephritis ESRD Rates Stable

The risk of end-stage renal disease in patients with systemic lupus erythematosus may even be declining, but outcomes differ by race.
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Over 100,000 Medicare Patients May Suffer from Glomerulonephritis

The condition appears to be associated with high hospitalization and death rates, researchers reported.
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Potential Plant-Derived Lupus Nephritis Treatment Has Few Side Effects

A plant-based compound could provide a new treatment for lupus nephritis with fewer side effects.
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Mortality in Lupus Patients Does Not Differ By Dialysis Type

Large study looked at matched pairs of lupus patients with renal disease starting dialysis with hemodialysis or peritoneal dialysis.
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Proteinuria Decline Linked to Improved Lupus Nephritis Outcomes

A 50% or greater reduction in proteinuria after six months of treatment for severe lupus nephritis predicted better 15-year renal survival.
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Lupus Nephritis Need Not Prevent Renal Transplants

Lupus nephritis patients can be good candidates if their disease is quiescent for at least one year prior to surgery.

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