Nephrology News

Fatigue Tied With Sorafenib, Sunitinib Use in Renal Cell Carcinoma

Although TKIs improve outcomes, they are still associated with toxicities common with cancer therapies, such as fatigue.
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Racial-Ethnic Gap in Living Donor Kidney Transplantation Widens

New findings suggest that national strategies have failed to correct racial/ethnic disparities in live donor kidney transplantation.
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Racial-Ethnic Gap in Living Donor Kidney Transplantation Widens

New findings suggest that national strategies have failed to correct racial/ethnic disparities in live donor kidney transplantation.
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Fatigue Tied With Sorafenib, Sunitinib Use in Renal Cell Carcinoma

Although TKIs improve outcomes, they are still associated with toxicities common with cancer therapies, such as fatigue.
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Early RRT for Acute Kidney Injury Not Superior

Early and late initiation of renal replacement therapy for AKI in critically ill patients are associated with similar long-term risks of death, chronic kidney disease, and end-stage renal disease.
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Total Kidney Volume in ADPKD Predicts CKD Progression

Each 100 mL/m increment in baseline height-adjusted total kidney volume is associated with 38% and 42% greater odds of developing stage 3 and 4 chronic kidney disease, respectively.
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Some High-risk Heart Failure Patients Benefit From MRAs

Mineralocorticoid receptor antagonists found to lower hospital readmission risk in patients with heart failure and concomitant diabetes or renal insufficiency.
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Pretreating Enteral Nutrition Effective for Pediatric Hyperkalemia

Pretreating enteral nutrition formula with sodium polystyrene sulfonate lowers potassium levels in hyperkalemic children with chronic kidney disease, small study finds.
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Antiretroviral Combo May Increase Kidney Disease Risk

CKD occurrence was seen in 3.4% of HIV patients receiving the combination of medications.
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Partial Nephrectomy Improves Survival in cT1b RCC Cases

Partial nephrectomy was associated with decreased odds of death versus radical nephrectomy among patients with cT1b but not cT2 renal cell carcinoma.
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FDA Approves Cabometyx for First-Line Treatment of Advanced RCC

Treatment with cabozantinib led to a clinically meaningful improvement in progression-free survival compared with sunitinib.
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Undocumented Immigrants Receiving Emergency HD More Likely to Die

The 5-year relative risk for mortality was 14-fold higher for undocumented immigrants receiving emergency-only versus standard hemodialysis.
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Phosphorus Content Higher in Packaged Meats Listing Phosphate Additives

Additives in packaged meat, poultry, and fish can contribute significantly to the dietary phosphorus and potassium loads in CKD patients, researchers say.
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Cytoreductive Nephrectomy Benefits for Metastatic RCC Demonstrated

Patients who underwent cytoreductive nephrectomy for metastatic non-clear cell renal cell carcinoma had a significantly decreased risk of cancer-related mortality.
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Cytoreductive Nephrectomy Benefits for Metastatic RCC Demonstrated

Patients who underwent cytoreductive nephrectomy for metastatic non-clear cell renal cell carcinoma had a significantly decreased risk of cancer-related mortality.
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Shift in HIV-Associated Kidney Disease Characterized

Antiretroviral therapies have prolonged the survival of HIV patients, but the drugs can have adverse effects on the kidneys.
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Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

In patients with stage 5 chronic kidney disease, lupus anticoagulant and combined thrombophilia occur more frequently in those with versus without calciphylaxis, case-control study shows.
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Kidney Cancer Bone Metastasis Predictors Id'd

Levels of alkaline phosphatase, calcium, and hemoglobin can independently predict bone metastasis in patients with renal cell carcinoma, Chinese investigators report.
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Tamsulosin Improves Clearance of Large Distal Ureteral Stones

Alpha blocker treatment resulted in a higher stone expulsion rate versus placebo in patients with distal ureteral stones larger than 5 mm in maximum diameter, study finds.
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Diabetic CKD Patients Survive Longer With Metformin

Diabetic patients with chronic kidney disease starting treatment with metformin have a 36% decreased risk of death compared with those starting on a sulfonylurea, study finds.
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